AI Viruses!

Scientists just used artificial intelligence to design the world's first AI-generated viruses capable of hunting down and killing drug-resistant strains of E. coli. These bacteriophages look like tiny alien pineapples with syringes that stab bacterial cells, and they're just the beginning of AI-created life. From Matt's dream of dish-cleaning bacteria that won't eat you (hopefully) to the accidental discovery that trying to make super purple petunias actually created white flowers instead, this episode explores what the if happens when computers start writing genetic code. Discover why we're running out of antibiotics, how a virus with only 11 genes works, and why your future dish soap bottle might say "now with AI inside." Plus, learn about the scientist who tried to engineer the most purple petunias ever and accidentally won a Nobel Prize instead.

Based on "World's First AI Designed Viruses: A Step Towards AI Generated Life" by Katie Kavanagh, published in Nature on September 19, 2025. https://www.nature.com/articles/d41586-025-03055-y

Matt also mentions a book worth checking out during the episode: "The Genealogy of a Gene: Patents, HIV/AIDS, and Race" by Myles W. Jackson, published by MIT Press. The book explores how intellectual property law has transformed scientific research through the fascinating story of the CCR5 gene, examining everything from Big Pharma to personalized medicine. Learn more at https://mitpress.mit.edu/9780262533782/the-genealogy-of-a-gene/

---

Check out our membership rewards! Visit us at Patreon.com/Whattheif

Got an IF of your own? Want to have us consider your idea for a show topic? Send YOUR IF to us! Email us at feedback@whattheif.com and let us know what's in your imagination. No idea is too small, or too big!

Keep On IFFin',
Philip, Matt & Gaby